Antibiotic growth promoters

Fresh belly characteristics and commercial bacon slicing yield in growing-finishing pigs fed an antibiotic-free diet or a diet supplemented with a natural antimicrobial

Lowell, J. E., B. M. Bohrer, K. B. Wilson, M. F. Overholt, B. N. Harsh, H. H. Stein, A. C. Dilger, and D. D. Boler. 2017. Fresh belly characteristics and commercial bacon slicing yield in growing-finishing pigs fed an antibiotic-free diet or a diet supplemented with a natural antimicrobial. J. Anim. Sci. 95(Suppl. 5):65 (Abstr.) Link to abstract (.pdf)

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Effects of antibiotic growth promoters in simple or complex diets fed to weanling pigs

Recently, the Food and Drug Administration announced that the number of antibiotic growth promoters that are available to be used by pigs will be reduced to reduce the risk of transferring antibiotic resistance from animals to humans. Only antibiotics that are not used in human medicine may be used as antibiotic growth promoters by animals in the future. To accommodate this change, it may be necessary to re-evaluate the use of antibiotic growth promoters in diets fed to pigs. It is possible that antibiotic growth promoters may be eliminated from swine diets if the complexity of the diets is increased. To test this hypothesis, an experiment was conducted to determine the effects of using an antibiotic growth promoter in diets formulated to vary in complexity.

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Preparing for the post-AGP era

By Dr. Hans H. Stein

December, 2013

On December 11, the Food and Drug Administration (FDA) announced a plan to limit the use of certain antimicrobials in food animals. The drugs at issue are those considered medically important in humans, including tetracyclines, penicillins and macrolides. The FDA's plan asks drug makers to voluntarily change the labels on their medically important antimicrobials to remove growth promotion as an indication. By law, drugs administered in animal feed cannot be used in a way inconsistent with their labeling, so this would effectively prohibit usage of antimicrobials as growth promoters. The FDA has also asked drug companies to revoke the targeted antimicrobials' over-the-counter status, so that a veterinarian's prescription would be required to use these medications for the purpose of disease prevention or treatment.

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Invited Review: Management and feeding strategies to ameliorate the impact of removing antibiotic growth promoters from diets fed to weanling pigs

Kil, D. Y., and H. H. Stein. 2010. Invited Review: Management and feeding strategies to ameliorate the impact of removing antibiotic growth promoters from diets fed to weanling pigs. Can. J. Anim. Sci. 90:447-460. Link to full text (.pdf)

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Effect of dietary carbadox on apparent ileal digestibility of amino acids in weanling pigs

Stewart, L. L., B. G. Kim, B.R. Gramm, R.D. Nimmo, and H.H. Stein. 2010. Effect of dietary carbadox on apparent ileal digestibility of amino acids in weanling pigs. Am. J. Anim. Vet. Sci. 5:168-174. Link to full text (.pdf)

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Reduced use of antibiotic growth promoters in diets fed to weanling pigs: Dietary tools, part 2

Stein, H. H., and D. Y. Kil. 2006. Reduced use of antibiotic growth promoters in diets fed to weanling pigs: Dietary tools, part 2. Anim. Biotechnol. 17:217-231. Link to full text (.pdf)

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Experience of feeding pigs without antibiotics - a European perspective

Stein, H. H. 2002. Experience of Feeding Pigs Without Antibiotics - a European perspective. Anim. Biotechnol, 13:85-95. Link to full text (.pdf)

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