Digestibility and metabolism of copper in diets for pigs and influence of dietary copper on growth performance, intestinal health, and overall immune status: a review

Espinosa, Charmaine D., and Hans H. Stein. 2021. Digestibility and metabolism of copper in diets for pigs and influence of dietary copper on growth performance, intestinal health, and overall immune status: a review. Journal of Animal Science and Biotechnology 12: 13. Link to full text.


Effects of dietary leucine and tryptophan supplementation on serotonin metabolism and growth performance of growing pigs

Tryptophan is an indispensable AA that is often limiting for growth in pigs fed corn-soybean meal-based diets. Tryptophan may act as a regulator of feed intake by enhancing serotonin signaling in the brain, because Trp is a precursor for serotonin. High Trp intake increases feed intake, and this is partly attributed to increased serotonin synthesis. Availability of dietary Trp in the brain is considered the rate-limiting step in hypothalamic serotonin synthesis. However, to be transported into the brain, Trp competes with other large neutral AA such as Val, Leu, Ile, Tyr, and Phe for a common transporter (L-type AA transporter 1) to cross the blood-brain barrier.

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