Gene expression

Effects of copper hydroxychloride on growth performance and abundance of genes involved in lipid metabolism of growing pigs

Supplementing Cu to diets fed to pigs at 100 to 250 mg/kg may reduce post-weaning scouring and also improve ADG and ADFI. Addition of Cu at 250 mg/kg in diets for pigs containing 5% animal fat improved growth performance, and it was speculated that this is due to the ability of Cu to improve animal fat utilization and enzymatic activity. Inclusion of 45 mg/kg of dietary Cu in diets for rabbits improved body mass gain by upregulating mRNA transcription of fatty acid transport protein, fatty acid binding protein, and carnitine palmitoyl transferase 1, indicating that dietary Cu may influence post-absorptive metabolism of lipids. However, the effect of supplementing dietary Cu on post-absorptive lipid metabolism in pigs remains inconclusive. Therefore, an experiment was conducted to test the hypothesis that addition of 150 mg/kg Cu from Cu hydroxychloride (IntelliBond CII; Micronutrients USA LLC; Indianapolis, IN) to a diet based on corn, soybean meal (SBM), and distillers dried grains with solubles (DDGS) improves growth performance of pigs, and that dietary Cu influences mRNA abundance of genes involved in post-absorptive metabolism of lipids in pigs.

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Effects of a 3 strain Bacillus-based direct-fed microbial and dietary fiber concentration on growth performance and expression of genes related to absorption and metabolism of volatile fatty acids in weanling pigs

Jaworski, N. W., A. Owusu-Asiedu, M. C. Walsh, J. C. McCann, J. J. Loor, and H. H. Stein. 2017. Effects of a 3 strain Bacillus-based direct-fed microbial and dietary fiber concentration on growth performance and expression of genes related to absorption and metabolism of volatile fatty acids in weanling pigs. J. Anim. Sci 95:308-319. Link to full text (.pdf)

Calcium transporters and gene expression and absorption of calcium in pigs

González-Vega, J. C. and H. H. Stein. 2016. Calcium transporters and gene expression and absorption of calcium in pigs. Pages 217-224 in Phytate destruction—consequences for precision animal nutrition. Walk, C. L., ed. Wageningen Academic Publishers, Wageningen, Netherlands. Link to full text 

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Requirement for digestible calcium by eleven- to twenty-five–kg pigs as determined by growth performance, bone ash concentration, calcium and phosphorus balances, and expression of genes involved in transport of calcium in intestinal and kidney cells

González-Vega, J. C., Y. Liu, J. C. McCann, C. L. Walk, J. J. Loor, and H. H. Stein. 2016. Requirement for digestible calcium by eleven- to twenty-five–kilogram pigs as determined by growth performance, bone ash concentration, calcium and phosphorus balances, and expression of genes involved in transport of calcium in intestinal and kidney cells. J. Anim. Sci. 94:3321-3334. Link to full text (.pdf)

Effect of a 3-Strain Bacillus-based direct-fed microbial on relative tissue gene expression in nursery and finishing pigs fed low- or high-fiber diets

Jaworski, N. W., M. C. Walsh, and H. H. Stein. 2016. Effect of a 3-Strain Bacillus-based direct-fed microbial on relative tissue gene expression in nursery and finishing pigs fed low- or high-fiber diets. J. Anim. Sci. 94(Suppl. 2):83 (Abstr.) Link to abstract (.pdf)

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