Most of the phosphorus in corn and other plant-based feed ingredients fed to pigs is bound to phytate. Pigs do not secrete phytase in adequate quantities to liberate significant amounts of phytate-bound phosphorus, meaning that most of the phosphorus in these ingredients is not biologically available. Calcium digestibility is also negatively affected by the presence of phytate in feed ingredients. One way for producers to ensure that pigs' requirements are met is to add supplementary phosphorus to diets. However, this adds to the cost of diets. The excretion of phytate-bound phosphorus also may contribute to algae overgrowth in waterways.
Another approach is to add supplemental phytase to the diets, to allow pigs to better utilize the phosphorus present in the ingredients. Phytases can be obtained from plants, animals, or microorganisms (bacteria, yeasts, and fungi).
GraINzyme is a source of phytase produced by genetically modified corn plants with genes derived from E. coli. In this experiment, the effect on growth performance, apparent total tract digestibility (ATTD) of calcium and phosphorus, and bone mineralization of adding GraINzyme to weanling pig diets was tested.